Pills, tablets and capsules can be properly disposed through the Cuyahoga County Sheriff's Office Rx Drug Drop Box Program. Residents can deposit unused, unwanted or expired prescription drugs at drop boxes located at law enforcement agencies throughout Cuyahoga County and all four campuses of Cuyahoga Community College. To find a drop off location, visit or call 2-1-1.

Needles and syringes are not accepted in the Drop Box. For proper disposal information, see 
Needles and Sharps.

Liquid medications are not accepted in the Sheriff's Rx Drop Box Program. Properly dispose of liquid medication by mixing it with something like coffee grounds, cat litter, dirt or sawdust to make it undesirable or unusable. Once the liquid is in unusable state, place it in the regular trash for proper disposal. Do not flush liquid medications into our sewer system or waterways. 

Contact your local police department or law enforcement agency about disposal of vaping products.


Our partners at the Northeast Ohio Regional Sewer District host seasonal Pitch Those Pills collection events. Due to COVID-19, there are no NEORSD collection events scheduled in 2021.

Seasonally, the U.S. DEA holds National Prescription Drug Take Back days to collect unwanted medications. Events are typically held in April and October. The next event is scheduled for October 23, 2021. Learn more.


Cleveland Clinic provides a safe method for disposal of medications that are expired or no longer needed. Cleveland Clinic has 14 drop boxes at its Northeast Ohio locations, including the Children’s Hospital, Euclid Avenue and Taussig Outpatient pharmacies at its main campus in Cleveland. The health system also has drop boxes at its family health centers and regional hospitals. See more about the medication disposal kiosks. Any approved prescription medications are accepted, including aerosols, liquids in sealed containers, tablets, capsules, creams and lotions. Disposal kiosks are available during regular pharmacy hours.

MetroHealth has public drop offs for unused prescription drugs at its Cleveland Heights and Parma medical centers. There are drop boxes located in the emergency rooms at each of those locations. See details.

Walgreens offers the Safe Medication Disposal Program. Drop-box receptacles at local Walgreens pharmacies are available during regular pharmacy hours. Locations in Cuyahoga County include:

Cleveland: 4265 State Road
Cleveland: 16803 Lorain Avenue
Euclid: 22401 Lake Shore Boulevard
Lakewood: 11701 Detroit Avenue
Parma: 5400 Pearl Road

CVS, Rite-Aid and other pharmacies offer mail-back programs for medications. Check at the in-store pharmacy for information about purchasing a pre-paid shipping envelope.


Consider donating usable insulin and unused diabetic supplies to Insulin for Life USA. 


Empty pill bottles larger than 3" in diameter can be recycled in your curbside recycling. Are you interested in donating smaller, unwanted pill bottles for reuse? Visit Matthew 25 Ministries for donation details.