Pills, tablets and capsules can be properly disposed through the Cuyahoga County Sheriff's Office Rx Drug Drop Box Program. Residents can deposit unused, unwanted or expired prescription drugs at drop boxes located at law enforcement agencies throughout Cuyahoga County and all four campuses of Cuyahoga Community College. To find a drop off location, visit or call 2-1-1.

Needles and syringes are not accepted in the Drop Box. For proper disposal information, see 
Needles and Sharps.

Liquid medications are not accepted in the Sheriff's Rx Drop Box Program. Properly dispose of liquid medication by mixing it with something like coffee grounds, cat litter, dirt or sawdust to make it undesirable or unusable. Once the liquid is in unusable state, place it in the regular trash for proper disposal. Do not flush liquid medications into our sewer system or waterways. 

Contact your local police department or law enforcement agency about disposal of vaping products.


Our partners at the Northeast Ohio Regional Sewer District host seasonal Pitch Those Pills collection events. In 2020, collection events will be held on the following dates at the listed Discount Drug Mart location from 10:00 AM - 2:00 PM.


Seasonally, the U.S. DEA holds National Prescription Drug Take Back days to collect unwanted medications. Learn more.


Cleveland Clinic provides a safe method for disposal of medications that are expired or no longer needed. Medication disposal kiosks are located in three outpatient pharmacies. Any approved prescription medications are accepted, including aerosols, liquids in sealed containers, tablets, capsules, creams and lotions. Disposal kiosks are available during regular pharmacy hours:
  • Cleveland Clinic Euclid Avenue Pharmacy, 1st Floor of Visitor Parking Garage #1, 9500 Euclid Avenue, Cleveland
  • Avon Ambulatory Pharmacy, 1st Floor, Richard E. Jacobs Health Center, 33100 Cleveland Clinic Blvd, Avon
  • Cleveland Clinic Hillcrest Hospital, 1st Floor Atrium, 6780 Mayfield Rd., Mayfield Heights
Walgreens offers the Safe Medication Disposal Program. Drop-box receptacles at three local Walgreens pharmacies are available during regular pharmacy hours. Locations in Cuyahoga County include:
Cleveland: 6410 Broadway Avenue
Euclid: 22401 Lake Shore Boulevard
Parma: 5400 Pearl Road

CVS, Rite-Aid and other pharmacies offer mail-back programs for medications. Check at the in-store pharmacy for information about purchasing a pre-paid shipping envelope.


Consider donating usable insulin and unused diabetic supplies to Insulin for Life USA. 


Empty pill bottles larger than 3" in diameter can be recycled in your curbside recycling. Are you interested in donating smaller, unwanted pill bottles for reuse? Visit Matthew 25 Ministries for donation details.