Medications In-home The Cuyahoga County Sheriff's Office provides an ongoing disposal option for meds. The Sheriff's RX Drug Drop Box Program allows residents to deposit unused, unwanted or expired prescription drugs at drop boxes in participating law enforcement agencies across Cuyahoga County. To find a drop off location visit www.RXdrugdropbox.com or call 2-1-1. Liquid medications cannot be disposed of via the Drop Box program at local law enforcement agencies. Do not flush them into our sewer system or waterways. Properly dispose of liquid medication by mixing with something like coffee grounds, cat litter or sawdust to make it undesirable or unusable. Once the liquid is in unusable state, place it in the regular trash. Walgreens offers the Safe Medication Disposal Program. Drop-box receptacles at three local Walgreens pharmacies are available during regular pharmacy hours. Locations in Cuyahoga County include: 6410 Broadway Avenue, Cleveland 22401 Lake Shore Boulevard, Euclid 5400 Pearl Road, Parma Needles are not accepted in the Drop Box. For proper disposal information, see Needles and Sharps.